{"id":6017,"date":"2019-12-22T10:47:19","date_gmt":"2019-12-22T10:47:19","guid":{"rendered":"https:\/\/www.dailyrounds.org\/blog\/?p=6017"},"modified":"2019-12-22T10:47:19","modified_gmt":"2019-12-22T10:47:19","slug":"mit-researchers-develop-a-novel-way-to-store-medical-records-under-the-skin","status":"publish","type":"post","link":"https:\/\/www.dailyrounds.org\/blog\/mit-researchers-develop-a-novel-way-to-store-medical-records-under-the-skin\/","title":{"rendered":"MIT researchers develop a novel way to store medical records under the skin"},"content":{"rendered":"<p><span data-preserver-spaces=\"true\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6019\" src=\"https:\/\/www.dailyrounds.org\/blog\/wp-content\/uploads\/2019\/12\/medical-records-gty-er-181025_hpMain_12x5_992.jpg\" alt=\"\" width=\"992\" height=\"415\" srcset=\"https:\/\/www.dailyrounds.org\/blog\/wp-content\/uploads\/2019\/12\/medical-records-gty-er-181025_hpMain_12x5_992.jpg 992w, https:\/\/www.dailyrounds.org\/blog\/wp-content\/uploads\/2019\/12\/medical-records-gty-er-181025_hpMain_12x5_992-300x126.jpg 300w, https:\/\/www.dailyrounds.org\/blog\/wp-content\/uploads\/2019\/12\/medical-records-gty-er-181025_hpMain_12x5_992-768x321.jpg 768w, https:\/\/www.dailyrounds.org\/blog\/wp-content\/uploads\/2019\/12\/medical-records-gty-er-181025_hpMain_12x5_992-500x209.jpg 500w\" sizes=\"auto, (max-width: 992px) 100vw, 992px\" \/>Soon, people can store their vaccination records in their body itself. Researchers are making progress in developing a novel way to record a patient&#8217;s vaccination history: storing the data in a pattern of dye, invisible to the naked eye, which is delivered under the skin at the same time as the vaccine.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">Though it has not been tested in the humans, work to date with rats and human cadaver skin has been promising. The new dye consists of nanocrystals called quantum dots, which can remain for at least five years under the skin, where it emits near-infrared light that can be detected by a specially equipped smartphone. The study has been published in\u00a0<\/span><a href=\"https:\/\/stm.sciencemag.org\/content\/11\/523\/eaay7162\"><em><span data-preserver-spaces=\"true\">Science Translational Medicine.\u00a0<\/span><\/em><\/a><\/p>\n<p><span data-preserver-spaces=\"true\">The copper-based dots are only about four nanometres in diameter but are encased in biocompatible microparticles that form spheres about 20 microns in diameter. This allows the dye to remain in place under the skin after being injected, the researchers say.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">The researchers designed their dye to be delivered by a microneedle patch rather than a traditional syringe and needle. Such patches are now being developed to deliver vaccines for measles, rubella, and other diseases, and the researchers showed that their dye could be easily incorporated into these patches.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">When the patch is applied to the skin, the microneedles, which are 1.5 millimetres long, partially dissolve, releasing their payload within about two minutes.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">By selectively loading microparticles into microneedles, the patches deliver a pattern in the skin that is invisible to the naked eye but can be scanned with a smartphone that has the infrared filter removed. The patch can be customized to imprint different patterns that correspond to the type of vaccine delivered.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">\u201cIt\u2019s possible someday that this \u2018invisible\u2019 approach could create new possibilities for data storage, biosensing, and vaccine applications that could improve how medical care is provided, particularly in the developing world,\u201d says Robert Langer, one of the senior authors of the study.\u00a0<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">The researchers now plan to survey health care workers in developing nations in Africa to get input on the best way to implement this type of vaccination record keeping. They are also working on expanding the amount of data that can be encoded in a single pattern, allowing them to include information such as the date of vaccine administration and the lot number of the vaccine batch.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">\u201cStorage, access, and control of medical records is an important topic with many possible approaches,\u201d says Mark Prausnitz, chair of chemical and biomolecular engineering at Georgia Tech, who was not involved in the research. \u201cThis study presents a novel approach where the medical record is stored and controlled by the patient within the patient\u2019s skin in a minimally invasive and elegant way,\u201d he adds.\u00a0<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">Source: MIT News, Cosmos Magazine.\u00a0<\/span><\/p>\n<div class=\"highwire-cite-title media__headline__title\">Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination<\/div>\n<p class=\"highwire-cite-authors byline\">BY <span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first\" data-delta=\"0\">KEVIN J. MCHUGH<\/span>, <span class=\"highwire-citation-author\" data-delta=\"1\">LIHONG JING<\/span>, <span class=\"highwire-citation-author\" data-delta=\"2\">SEAN Y. SEVERT<\/span>, <span class=\"highwire-citation-author\" data-delta=\"3\">MACHE CRUZ<\/span>, <span class=\"highwire-citation-author\" data-delta=\"4\">MORTEZA SARMADI<\/span>, <span class=\"highwire-citation-author\" data-delta=\"5\">HAPUARACHCHIGE SURANGI N. JAYAWARDENA<\/span>, <span class=\"highwire-citation-author\" data-delta=\"6\">COLLIN F. PERKINSON<\/span>, <span class=\"highwire-citation-author\" data-delta=\"7\">FRIDRIK LARUSSON<\/span>, <span class=\"highwire-citation-author\" data-delta=\"8\">SVIATLANA ROSE<\/span>, <span class=\"highwire-citation-author\" data-delta=\"9\">STEPHANIE TOMASIC<\/span>, <span class=\"highwire-citation-author\" data-delta=\"10\">TYLER GRAF<\/span>, <span class=\"highwire-citation-author\" data-delta=\"11\">STEPHANY Y. TZENG<\/span>, <span class=\"highwire-citation-author\" data-delta=\"12\">JAMES L. SUGARMAN<\/span>, <span class=\"highwire-citation-author\" data-delta=\"13\">DANIEL VLASIC<\/span>, <span class=\"highwire-citation-author\" data-delta=\"14\">MATTHEW PETERS<\/span>, <span class=\"highwire-citation-author\" data-delta=\"15\">NELS PETERSON<\/span>, <span class=\"highwire-citation-author\" data-delta=\"16\">LOWELL WOOD<\/span>, <span class=\"highwire-citation-author\" data-delta=\"17\">WEN TANG<\/span>, <span class=\"highwire-citation-author\" data-delta=\"18\">JIHYEON YEOM<\/span>, <span class=\"highwire-citation-author\" data-delta=\"19\">JOE COLLINS<\/span>, <span class=\"highwire-citation-author\" data-delta=\"20\">PHILIP A. WELKHOFF<\/span>, <span class=\"highwire-citation-author\" data-delta=\"21\">ARI KARCHIN<\/span>, <span class=\"highwire-citation-author\" data-delta=\"22\">MEGAN TSE<\/span>, <span class=\"highwire-citation-author\" data-delta=\"23\">MINGYUAN GAO<\/span>, <span class=\"highwire-citation-author\" data-delta=\"24\">MOUNGI G. BAWENDI<\/span>, <span class=\"highwire-citation-author\" data-delta=\"25\">ROBERT LANGER<\/span>, <span class=\"highwire-citation-author\" data-delta=\"26\">ANA JAKLENEC<\/span><\/span><\/p>\n<p class=\"highwire-cite-metadata byline\"><em>SCIENCE TRANSLATIONAL MEDICINE\u00a0<\/em><time>18 DEC 2019<\/time><\/p>\n<p class=\"highwire-cite-metadata byline\">\n","protected":false},"excerpt":{"rendered":"<p>Soon, people can store their vaccination records in their body itself. Researchers are making progress in developing a novel way to record a patient&#8217;s vaccination history: storing the data in a pattern of dye, invisible to the naked eye, which is delivered under the skin at the same time as the vaccine. Though it has [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":6019,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[5],"tags":[26,694,183],"class_list":["post-6017","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-medical","tag-skin","tag-world-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>MIT researchers develop a novel way to store medical records under the skin - DailyRounds<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dailyrounds.org\/blog\/mit-researchers-develop-a-novel-way-to-store-medical-records-under-the-skin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MIT researchers develop a novel way to store medical records under the skin - DailyRounds\" \/>\n<meta property=\"og:description\" content=\"Soon, people can store their vaccination records in their body itself. 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